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Letter

Chronic psychological stress and cardiovascular disease risk: When to use single biomarkers versus allostatic load

Details

Citation

Chauntry AJ, Whittaker AC, Puterman E, Seeman T, Teychenne M, Turner AI, Zieff G, Logan JG & Stoner L (2025) Chronic psychological stress and cardiovascular disease risk: When to use single biomarkers versus allostatic load. Progress in Cardiovascular Diseases. https://doi.org/10.1016/j.pcad.2025.02.005

Abstract
First paragraph: To the Editor We read with interest recent papers in Progress in Cardiovascular Diseases related to psychological stress and cardiovascular disease (CVD). These papers discuss the role of psychological stress in CVD etiology, highlighting the importance of dysregulation to the biological stress response system. Despite the increased awareness of the stress-activated biological system over the past decade, significant knowledge gaps persist, likely stemming from inconsistent and inadequate measurements of biological stress response dysregulation. Below we confer important recommendations for measuring stress-induced biological dysregulation, focusing on when to use the individual biomarker approach versus the allostatic load model. Fig. 1 illustrates the key concepts discussed in this paper, with boxes labeled A to E corresponding to the headings below.

Journal
Progress in Cardiovascular Diseases

StatusEarly Online
Publication date online28/02/2025
Date accepted by journal08/02/2025
PublisherElsevier BV
ISSN0033-0620

People (1)

Professor Anna Whittaker

Professor Anna Whittaker

Professor of Behavioural Medicine, Sport