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Citation

Elahwl EA, Assar DH, Al-Hawary II, Salah AS, Ragab AE, Elsheshtawy A, Assas M, Abo-Al-Ela HG, Fouad AM & Elbialy ZI (2025) Alleviation of glyphosate-induced toxicity by Horseradish tree?(Moringa oleifera) Leaf extract and phytase in Nile Tilapia (Oreochromis niloticus) highlighting the antioxidant, anti-inflammatory, and anti-apoptotic activities. Veterinary Research Communications, 49, Art. No.: 135. https://doi.org/10.1007/s11259-025-10672-5

Abstract
The danger posed by waterborne toxicity from herbicides endangers the aquatic ecosystem. Using dietary medicinal herbs is a useful approach to mitigate the effects of herbicide toxicity on aquatic animals. This study attempts to examine the consequences and potential mechanisms behind the dietary addition of horseradish tree (Moringa oleifera) leaf extract (MOLE) with the help of phytase addition to check the overall growth performance, biochemical changes, histological alteration, and gene expression in normal and after glyphosate challenge in Nile tilapia. A total number of 135 Nile tilapia fish (7.93 0.03 g) were randomly assigned into three groups each in triplicate. The first group is the control group and fed basal diet; the second group supplied with MOLE (200 mg of extract/kg), and the third group was supplied with MOLE (200 mg /kg), and phytase (0.2g/ kg) for 8 weeks. After the feeding trial, each experimental group was divided into two subgroups to be unchallenged and challenged with glyphosate (30 mg/L of water). The results declared significant enhancements (P?

Keywords
Horseradish; Glyphosate; Phytase; Nile tilapia

Journal
Veterinary Research Communications: Volume 49

• Published Version